Posters

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P1 – Investigating the Mg2+ cations influence on the formation of RNA Kissing complexes

Josephine Abi-Ghanem^1,2,3, Clémence Rabin^1,2,3, Massimiliano Porrini^1,2,3, Valérie Gabelica^1,2,3

P2 – From DNA Computation to Aptamer Selection: Beyond the Hopfield approximation.

Dr. Jean-Pierre Aimé, Dr Juan Elezgaray.

P3 – Aptaswitches: new supramolecular tools

1. Bonnet-Salomon, E. Dausse, G. Durand, J.-J. Toulmé and L. Azéma

P4 – Targeted anticancer therapy using bioconjugates of magnetic nanoparticles with DNA-aptamers

Irina.V. Belyanina^1,2,3, Anna Zamay^1,2, Galina S. Zamay^1,2, Yury E. Glazyrin², Olga S. Kolovskaya^1,2, Taiana Ivanchenko¹, Dmitry Veprincev^1,2, Alexey E. Sokolov¹, Valery Denisenko¹, Sergey Zamay¹, Maxim Berezovski⁴, scientific adviser dr. Tatiana N. Zamay

P5 – Development of synthetic riboswitches.

Adrien Boussebayle, Thea Lotz, Beatrix Süß.

P6 – An Aptamer-Based Diagnostic Test Specific for Falciparum Malaria

Yee-Wai Cheung¹, Roderick M. Dirkzwager¹, Josiane Cardoso², Alvin Wai-Chung Wong¹ and Julian A. Tanner¹

P7 – RNA aptamers as ligands of integrin alpha5 beta1

Marine Fenat¹, Pierre Fechter², Nelly Etienne-Selloum¹, Isabelle Lelong-Rebel¹, Sophie Martin¹, Maxime Lehmann¹, Monique Dontenwill¹ & Laurence Choulier¹

P8 – ELAKCA: Enzyme-Linked Aptamer Kissing Complex Assay as a Small Molecule Sensing Platform

Benoit Chovelon,^1,2 Guillaume Durand,³ Eric Dausse,³ Jean-Jacques Toulmé,³ Patrice Faure,^2,4 Eric Peyrin^1* and Corinne Ravelet^1*

P9 – Near infrared fluorescent imaging for aptamers biodistribution

Ioanna Theodorou^1,2, Chloé Dambrune^1,2, Nam Nguyen Quang^1,2, Benoit Lelandais^1,2, Frederic Ducongé^1,2

P10 – Identification of DNA kissing complexes.

Eric Dausse, Nicolas J. Tourasse and Jean-Jacques Toulmé

P11 – Riboswitches based on kissing complexes for the detection of small ligands

Durand Guillaume^1,2, Eric Dausse², Corinne Ravelet³, Eric Peyrin³, Jean-Jacques Toulmé^2,4

P12 – Riboswitch – Small Molecule Interactions Analyzed with the switchSENSE Platform

Felix Kroener^1,2, Christopher Schneider³, Florian Groher³, Beatrix Süß³, Wolfgang Kaiser¹

P13 – A novel internalizing Aptamer Targeting Insulin Receptor

Margherita Iaboni ^1,4, Raffaela Fontanella², Anna Rienzo³, Maria Capuozzo³, Nuzzo S.^{1, 3}, Silvia Catuogno³, Gerolama Condorelli ^1,3, Vittorio de Franciscis³, Carla Lucia Esposito³

P14 – Single cell-level microsurgery using aptamer functionalized magnetic microdiscs for tumor eradicationIrina Garanzha, ^a,c, Anna Zamay^a,b, Galina S. Zamay^a,b, Yury E. Glazyrin^b, Olga S. Kolovskaya^a,b, Alexandr Shabanov^a, Viktor Y. Prinz^e, Vladimir Seleznev^e, Tatiana Ivanchenko^b, Dmitry Veprincev^a,b, Alexey E. Sokolov^a, Valery Denisenko^a, Sergey Zamay^a, Ana Gargaun^d, Maxim Berezovski^d, scientific adviser dr. Tatiana N. Zamay

P15 – Colorimetric small molecules sensing using a structure switching strategy on modified gold nanoparticles

Emma Goux¹, Valérie Guieu¹*, Luc Choisnard¹, Guillaume Durand², Eric Dausse², Jean-Jacques Toulmé², Corinne Ravelet¹ and Eric Peyrin¹

P16 – Kinetic analysis of the different candidate RNA aptamers-protein interactions

Nathalie Vollmer¹, Karen Mercier¹, Fatima-Ezzahra Hibti¹, Xianbin Yang², Mark Shumbera², Marinella Sandros³, Chiraz Frydman¹

P17 – Subtractive cell SELEX for DNA aptamers binding to a human leukemia cell line.

NA Kacherovsky¹, BR Olden¹, SJ Salipante², MC Jensen³, SH Pun¹

P18 – Nuclease-Activated Oligonucleotide Probes for the Rapid and Robust Detection of Breast Cancer Circulating Tumor Cells (CTCs)

Sven Kruspe¹, David D. Dickey¹, William H. Thiel¹, Karen C. Clark¹, Kevin Urak², Elliot Burghardt¹, Justin P. Dassie¹, Alexandra Thomas¹, James O. McNamara II^1,2, Paloma H. Giangrande^1,2,3.

P19 – Quantification of non-coding RNAs in bacterial cells

using a Broccoli aptamer

Charlotte Hardion, Alexandre Dawid, Stéphan Lacour

P20 – The skin: a novel field for therapeutic aptamers

Thomas Lettner, Julia Reichelt, Verena Wally.

P21 – Development of aptamer-based electrochemical sensing system for monitoring luteinizing hormone pulsatility

Shaolin Liang^{1, 2}, Waljit Dhillo², Anthony E G Cass³ and Julian A Tanner¹

P22 – Aptamers Binding To Bradykinin

Ricardo Lima Pereira, Arquimedes Cheffer, Claudiana Lameu, Ana Paula Santos, Henning Ulrich

P23 – CE-non-SELEX for the isolation of aptamers directed against the tau protein.

Samuele Lisi^1,2, Emmanuelle Fiore¹, Yannik Boehmann³, Simona Scarano², Maria Minunni², Eric Peyrin¹, Corinne Ravelet¹

P24 – Experimental conditions affect apparent affinity of thrombin-binding DNA aptamers

Kepler Mears¹, Delia J. Scoville¹, Rebecca J. Whelan¹

P25 – MicroScale Thermophoresis: Interaction Analysis and beyond

Moran Jerabek-Willemsen, Timon André, Randy Wanner, Heide Marie Roth, Stefan Duhr, Philipp Baaske, Dennis Breitsprecher

P26 – Identification of Stem Cell Lung Cancer by DNA Aptamers

Isis C. Nascimento¹, Jan Mavri², Tina Smuc², Arthur A. Nery¹, Tamara T. Lah³, Matjaz Peterka², Henning Ulrich¹

P27 – Selection of Specific, Slow Off-rate Modified Aptamer (SOMAmer^®) Reagents for the Highly Similar Proteins GDF-11 and GDF-8

Urs Ochsner¹, Louis Green¹, Taylor Rice¹, and Nebojsa Janjic¹

P28 – An RNA aptamer that binds the glycolytic flux-signaling metabolite

Fructose-1,6-bisphosphate.

Alvaro D. Ortega¹, Yi Long², Neus Mestre-Farràs¹, Franziska Pfeiffer³, Günter Mayer³, Lars Folke Olsen², Matthias Heinemann¹.

P29 – Targeting CD28 costimulation with bi-specific aptamers to melanoma chemotherapy resistant cancer stem cells.

Mario M Soldevilla^1,2, Helena Villanueva^1,2, Noelia Casares^2,3, Juan J Lasarte^2,3, Maurizio Bendandi⁴, Susana Inoges^2,5, Ascension López-Díaz de Cerio^2,5, Fernando Pastor^1,2.

P30 – Preclinical trials of novel anticoagulant — DNA aptamer Trombiveb®.

Galina V. Pavlova^1,2, Alexey M. Kopylov^1,3, Askar D. Turashev¹, Nadezhda S. Samoylenkova^1,2, Elena G. Zavyalova^1,3, Alexander V. Revishchin², Andrey V. Golovin^1,4.

P31 – Biophysical characterization of RNA-metabolite complexes by native MS

Stefano Piccolo ^1,2,3 et Valérie Gabelica ^1,2,3

P32 – Semi-automated binding of aptamers on adherent living cells

Nam Nguyen Quang^{1, 2}, Carine Pestourie³, Agnès Cibiel⁴ & Frédéric Ducongé^{1, 2,*}

P33 – PATTERNITY-seq: high-throughput analysis of sequence patterns and paternity relationship between them during molecular evolution processes.

Nam Nguyen Quang^1,2, Clément Bouvier^1,2, Benoit Lelandais^1,2 and Frédéric Ducongé^1,2.

P34 – A native MS Study of RNA kissing complexes and their interaction with magnesium cations

Clémence Rabin ^1,2,3, Adrien Marchand^1,2,3, Joséphine Abi-Ghanem^1,2,3 & Valérie Gabelica^1,2,3

P35 – Functional neutralization of αC-conotoxin PrXA by aptamers

Tarek Mohamed Abd El Aziz^{1, 3}, Corinne Ravelet^2* , Emmanuelle Fiore² , Germain Sotoing Taiwe⁵, Michel Ronjat¹, Jerôme Dejeu⁴, Eric Peyrin^2, , Michel De Waard^{1, 6}

P36 – Aptamers for identification and purification of mesenchymal stem cells

Ana Paula Santos¹ ; Arthur A. Nery¹ ; Henning Ulrich¹

P37 – Selection of aptamers against the norovirus protruding domain in presence of four different food matrices

Katja Schilling^1,2, Jacquelina Woods²

P38 – Characterization of aptaswitch complexes by MicroScale Thermophoresis.

Thomas Schubert¹ , Eric Dausse², Kniep Lukas¹, Guillaume Durand², Jean-Jacques Toulmé².

P39 – Selecting DNA Aptamers for the Ovarian Cancer Biomarker CA125

Delia Scoville¹, Tae Kyu Brian Uhm¹, Jamie Shallcross¹, Rebecca Whelan¹

P40 – Aptamer-Mediated Macromolecular Recognitionin Facilitating DNA Tweezer Machinery

Simon Chi-Chin Shiu, Yee-Wai Cheung, Roderick M. Dirkzwager, Shaolin Liang,

Andrew B. Kinghorn, Lewis A. Fraser, Marco S. L. Tang and Julian A. Tanner

P41 – Efficient Cell-SELEX using engineered isogenic cell lines to generate RNA aptamer against a cell surface protein of interest

Masaki Takahashi¹, Yoshifumi Hashimoto¹, Eri Sakota¹, Yoshikazu Nakamura^1,2

P42 – Aptamer-gated DNA origami nanobox for malaria detection

Marco S. L. Tang¹, Maia Godonoga², Andrew B Kinghorn¹, Yee-Wai Cheung¹, Jonathan Heddle³

and Julian A. Tanner¹

P44 – Control of pre-mRNA splicing by the tetracycline aptamer

Marc Vogel¹, Julia E. Weigand¹, Beatrix Süß¹

P45 – Multiplex aptamer-based electrochemical sensor for lung cancer detection.

Galina S. Zamay^1,2, Yury E. Glazyrin^1,2, Tatiana N. Zamay¹, Vasilii A. Kolovsky⁷, Alexandr V. Shabanov³, Dmitry V. Veprintsev¹, Alexey V. Krat⁴, Sergey S. Zamay³, Olga S. Kolovskaya¹, Ana Gargaun⁶, Alexey E. Sokolov⁵, Andrey A. Modestov⁴, Ivan P. Artyukhov¹, Nikolay V. Chesnokov², Marina M. Petrova¹, Maxim V. Berezovski⁶, Anna S. Zamay*^1,2  

P46 – Selective elimination of tumor cells in vivo using laser induced plasmon resonance of aptamer functionalized gold nanoparticles

Tatiana. N Zamay^a,b, Irina.V. Belyanina^b,d, Alexandr Alexandrovskii^a, Alexey E. Sokolov^a, Dubinina Anna^a, Galina S. Zamay^a,b, Irina Garanzha^d, Yury E. Glazyrin^b, Olga S. Kolovskaya^b, Tatiana Ivanchenko^b, Natalia Chanchikova^c, Nikolay Tokarev^c, Nikolay Shepelivich^c, Elena Karlova^c, Anastasia Ozerskaya^c, Evgeniy Badrin^c, Kirill Belugin^c, Semion Belkin^c ,Vladimir Zabluda^a, Maxim Berezovski^e, Anna Zamay^b

P47 – INTERFERING WITH THE PROLIFERATION OF PLASMODIUM FALCIPARUM BY CELL-SELEX

Flávia Zimbres¹, Henning Ulrich², Carsten Wrenger¹

P48 – Generating aptamers capable of binding small molecular targets and refining the target binding characteristics

Shalen Kumar^1,2, Shiwei Li^1,2, Jeremy Jones¹, Doug C. Eckery³, Janet Pitman¹ and Kenneth P. McNatty¹

P49 – Identification of glioblastoma stem-like cells by DNA aptamers

Erika de S. Molina¹, Tiago Sobreira², Marina Trombetta-Lima³, Lucas Nishida¹, Maria Elisa Goes¹, Attila Tárnok⁴, Heidrun Holland⁴, Isis C. Nascimento¹, Mari Cleide Sogayar³, Henning Ulrich¹

P50 – Use of aptamers as antitumor agents based on Cell Selex methodology for prostate cancer

Aline Moreira¹, Anael Alberto¹, Helena Magalhães¹, Leila Mendonça¹, Etel Gimba², Martin Bonamino^3,4, Wim Degrave¹ and Mariana Waghabi¹

P51 – Conditional aptaswitch interaction.

Lorena Zara¹, Eric Dausse¹, and Jean-Jacques Toulmé^1,2

P52 – Switch Aptamers-Based Analysis: A Promising Alternative for Mycotoxins Detection

Gaëlle Catanante¹, Atul Sharma², K. Yugender Goud³, and Jean-Louis Marty¹

P53 – Aptamer selection by microfluidic recovery coupled with SPR detection

Carmelo Di Primo^1,2, Eric Dausse^1,2, Aurélien Barré³, Alain Rico⁴, Emilie Daguerre^1,2, Gilmar Salgado^1,2, Macha Nikolski³ and Jean-Jacques Toulmé^1,2

P54 – Just in Time-Selection: A semiautomated two-step method for in vitro selection of DNA aptamers
Fischer

P55 – Tunable Cytotoxic Agents for the Treatment of Prostate Cancer

Bethany Powell Gray¹, Linsley Kelly², Jessica McDade¹, Matthew Levy², and Bruce A. Sullenger^1,3

P56 – Fluid Biopsy Allowing Lung Cancer Diagnosis via Aptamer Based CTC Detection

V.L. Grigoreva^1,3, Galina S. Zamay^1,2, Anna Zamay^1,2 , Yury E. Glazyrin², Olga S. Kolovskaya^1,2, Alexey V Krat^1,2, Irina Garanzha^1,3, Ana Gargaun⁴, Marina Petrova², Ivan Artyukhov², Maxim Berezovski⁴, scientific adviser dr. Tatiana N. Zamay

P57 – Active and Exo-site Inhibition of Factor Xa by RNA Aptamer-Drug Pairs for Potent, Reversible Anticoagulation

Ruwan Gunaratne¹, James Frederiksen¹, Michelle D. Ho², Nabil K. Thalji², Rodney M. Camire², and Bruce A. Sullenger¹

P58 – Small-Molecule Detection and Enantiopurity Measurement Using DNA-Based Sensors.

Jennifer Heemstra¹, Trevor Feagin¹, Amberlyn Peterson¹, and Zhesen Tan¹

P59 – Expanding the Chemical Diversity of DNA

Chun Guo¹, Dehui Kong¹, Yi Lei¹, and Ryan Hili¹

P60 – DNA-aptamers as synthetic molecular probes for staining of abnormal blood vessels and tumor cells in lung cancer tissue sections

Olga S. Kolovskaya^1,2, Galina S. Zamay^1,2, Tatiana Ivanchenko², Tatiana N. Zamay¹, Valentina Grigorieva¹, Maxim V. Berezovski³, and Anna S. Zamay^1,2

P61 – Fitness Landscapes of Functional RNAs

Ádám Kun^1,2,3 and Eörs Szathmáry^1,3,4

P62 – FNA fluorescence reporting within silica-zirconia porous thin films

Marine Le Goas¹, Nina Landreau¹, Valérie Guieu², Corinne Ravelet², Eric Peyrin², Serge Palacin¹ and Laurent Mugherli¹

P63 – Asymmetric inhibition of a small chiral molecule/aptamer binding reaction upon aptamer modification: a kinetic study using rotating droplet electrochemistry

Lylian Challier^1‡, Rebeca Miranda-Castro^1‡, Claire Fave², Benoît Limoges², François Mavré², and Vincent Noël¹

P64 – Selection of DNA aptamers from libraries of G-rich sequences as potential therapeutic agents in HMGB1-related pathologies

Domenica Musumeci^1,3, Carla L. Esposito², Giovanni N. Roviello³, Angela Coppola¹, Vittorio De Franciscis², Claudia Riccardi¹, Chiara Platella¹, and Daniela Montesarchio¹

P65 – Ultrasensitive and rapid detection combining aptamers and isothermal recombinase polymerase amplification

Miriam Jauset-Rubio¹, Markéta Svobodová¹, Teresa Mairal¹, Mohammad S. El-Shahawi³, Abdulaziz S. Bashammakh ³, Abdulrahman O. Alyoubi³, and Ciara K. O´Sullivan ^1,3

P66 – Small Molecule Aptamer Assays Based on Fluorescence Anisotropy Signal-Enhancer Oligonucleotides

Sandrine Perrier, Prisca Bouilloud, Gisella De Oliveira Coelho, Mickael Henry and Eric Peyrin

P67 – Strategy of enhanced fluorescence polarization based on aptamer – protein anchor complexes for sensitive and rapid detection of ochratoxin A

Irina V. Safenkova¹, Alexey V. Samokhvalov¹, Sergei A. Eremin², Anatoly V. Zherdev¹, and Boris B. Dzantiev¹

P68 – Targeting Structured RNAs via Cross-Chiral Recognition

Jonathan T. Sczepanski¹

P69 – Development of an Antidote-Controlled RNA Probe for Molecular Thrombi Imaging

Kady-Ann Steen-Burrell¹, Bethany Powell Gray¹, and Bruce Sullenger¹