[vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column width=”1/3″][vc_empty_space height=”25px”][/vc_column][vc_column width=”1/3″][vc_single_image image=”1788″ img_size=”300″ alignment=”center” onclick=”custom_link” qode_css_animation=”” link=”http://www.aptamersinboulder.com/wp-content/uploads/2018/08/Aptamers-Program2018.pdf” el_id=”program”][vc_column_text]
Click to download the 2018 Final Symposium Program
[/vc_column_text][vc_empty_space height=”25px”][/vc_column][vc_column width=”1/3″][vc_empty_space height=”25px”][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_column_text]
[/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_empty_space height=”25px”][vc_separator type=”normal” color=”#303030″ thickness=”1″][vc_empty_space height=”25px”][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_column_text css=”.vc_custom_1530145333437{margin-bottom: 10px !important;}”]
[/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_empty_space height=”25px”][vc_separator type=”normal” color=”#303030″ thickness=”1″][vc_empty_space height=”25px”][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_column_text]8:00 — Registration and breakfast
[/vc_column_text][vc_column_text]8:30 – 8:45 — Opening Remarks
Larry Gold
[/vc_column_text][vc_empty_space][vc_column_text css=”.vc_custom_1532885585497{margin-bottom: 10px !important;}”]8:45 – 9:30 –Expanding Aptamer Chemistries and Applications
Andrew Ellington, Fraser Professor of Biochemistry, University of Texas at Austin
[/vc_column_text][vc_empty_space][vc_column_text css=”.vc_custom_1532885639372{margin-bottom: 10px !important;}”]9:30 – 10:15 – From Phage Biology to Human Health: a Purposeful Walk Through Randomness
Nebojsa Janjic
[/vc_column_text][vc_empty_space][vc_column_text css=”.vc_custom_1530145844804{margin-bottom: 10px !important;}”]10:15 – 10:45 – Heterochiral Nucleic Acid Technologies
Jonathan Sczepanski, Assistant Professor, Texas A&M University
[/vc_column_text][vc_empty_space][vc_column_text css=”.vc_custom_1530145151146{margin-bottom: 10px !important;}”] 10:45 – 11:15 – Break[/vc_column_text][vc_empty_space][vc_column_text css=”.vc_custom_1530145857982{margin-bottom: 10px !important;}”]11:15 – 11:40 – From Aptamer Structure to Application: Combination of Factor Xa aptamer and small molecule active site inhibitor are potent and reversible anticoagulants for cardiopulmonary bypass surgery,
Bruce Sullenger, Professor of Surgery, Associate Professor in Molecular Genetics and Microbiology, Professor of Pharmacology and Cancer Biology, Duke University
[/vc_column_text][vc_empty_space][vc_column_text css=”.vc_custom_1530145869757{margin-bottom: 10px !important;}”]11:40 – 12:00 – Therapeutic Aptamers Based on 2-Fully Modified RNAs and Novel Selection Strategies
Rihe Liu, Associate Professor, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill
[/vc_column_text][vc_empty_space][vc_column_text css=”.vc_custom_1530145882060{margin-bottom: 10px !important;}”]12:00 – 12:45 – A Short History of RNA Structure
Tom Cech, Distinguished Professor, University of Colorado Boulder; Director, BioFrontiers Institute
[/vc_column_text][vc_empty_space][vc_column_text css=”.vc_custom_1530145465617{margin-bottom: 10px !important;}”]12:45 – 2:00 – Lunch[/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_empty_space height=”25px”][vc_separator type=”normal” color=”#303030″ thickness=”1″][vc_empty_space height=”25px”][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_column_text css=”.vc_custom_1530145604837{margin-bottom: 10px !important;}”]
[/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_empty_space height=”25px”][vc_separator type=”normal” color=”#303030″ thickness=”1″][vc_empty_space height=”25px”][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_column_text]2:00 – 2:30 — Creating Efficiencies and Establishing Reproducible Research in Insight Discovery
Kirk DeLisle, Director of Bioinformatics, SomaLogic
[/vc_column_text][vc_empty_space][vc_column_text]2:30 – 3:00 — AptaSUITE – A Bioinformatics Framework for the Comprehensive Analysis of HT-SELEX Experiments
Jan Hoinka, National Center of Biotehcnology Information, National Library of Medicine, NIH
[/vc_column_text][vc_empty_space][vc_column_text]3:00 – 3:30 — Graphical Analysis of High-Throughput Sequencing Data to Study the Molecular Evolution of Aptamers
Frédéric Ducongé, Scientist, CEA, DRF, Institute François Jacob, MIRCen
[/vc_column_text][vc_empty_space][vc_column_text]3:30 – 4:00 — Break[/vc_column_text][vc_empty_space][vc_column_text]4:00 – 4:30 — Engineering Functional Xeno Nucleic Acids Using Synthetic Genetics
Alex Taylor, Investigator Scientist, MRC laboratory of Molecular Biology
[/vc_column_text][vc_empty_space][vc_column_text]4:30 – 4:50 — Tunable Cytotoxic Agents for the Treatment of Prostate Cancer
Bethany Powell Gray, Duke University Medical Center
[/vc_column_text][vc_empty_space][vc_column_text]4:50 – 5:15 — Highly Efficient Expression of Circular RNA: A Novel Platform for RNA Synthetic Biology
Jacob Litke, Weill Cornell Medicine, PhD Candidate
[/vc_column_text][vc_empty_space][vc_column_text]5:15 – 6:00 — RNA Aptamers as Genetic Control Devices – the Potential of Riboswitches as Synthetic Elements for Regulating Gene Expression
Beatrix Suess, Professor, Chemical and Synthetic Biology, Technical University Darmstadt, Germany
[/vc_column_text][vc_empty_space][vc_column_text]6:00 — Poster Session[/vc_column_text][vc_column_text css=”.vc_custom_1521134881552{margin-bottom: 10px !important;}”][/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_empty_space height=”25px”][vc_separator type=”normal” color=”#303030″ thickness=”1″][vc_empty_space height=”25px”][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column width=”1/4″][vc_column_text]8:00 pm[/vc_column_text][/vc_column][vc_column width=”3/4″][vc_column_text css=”.vc_custom_1530134214280{margin-bottom: 10px !important;}”]
[/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_empty_space height=”25px”][vc_separator type=”normal” color=”#303030″ thickness=”1″][vc_empty_space height=”25px”][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_column_text]
[/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_empty_space height=”25px”][vc_separator type=”normal” color=”#303030″ thickness=”1″][vc_empty_space height=”25px”][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_column_text css=”.vc_custom_1530193738439{margin-bottom: 10px !important;}”]
[/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_column_text css=”.vc_custom_1521135296680{margin-bottom: 10px !important;}”][/vc_column_text][vc_column_text]8:00 – Breakfast[/vc_column_text][vc_column_text]8:30 – 8:45 – Opening Remarks
Jean-Jacques Toulmé
[/vc_column_text][vc_empty_space][vc_column_text]8:45 – 9:30 – Are Aptamers in Dicer’s Future?
Brenda Bass, Distinguished Professor, H.A and Edna Benning Presidential Endowed Chair, Dept. of Biochemistry, University of Utah
[/vc_column_text][vc_empty_space][vc_column_text]9:30 – 10:00 – A Multi-Color Riboswitch-Based Platform for Live Cell Imaging of RNA in Mammalian Cells
Esther Braselmann, University of Colorado Boulder, Department of Biochemistry and BioFrotiers Institute
[/vc_column_text][vc_empty_space][vc_column_text]10:00 – 10:30 – A Light Dependent Aptamer-Photoreceptor System for the Control of RNA Function in Cells
Günter Mayer, University of Bonn
[/vc_column_text][vc_empty_space][vc_column_text]10:30 – 11:00 – Break[/vc_column_text][vc_empty_space][vc_column_text]11:00 – 11:30 – RNA Inhibitors of Nuclear Proteins Responsible for Multiple Organ Dysfunction Syndrome
Paloma Giangrande, Associate Professor of Internal Medicine – Hematology, Oncology and Blood and Marrow Transplantation
Associate Professor of Radiation Oncology, University of Iowa
[/vc_column_text][vc_empty_space][vc_column_text]11:30 – 12:00 – Aptamer-STAT3-RNA bio-drugs as novel tool to eradicate glioblastoma stem-like cells
Vittorio De Franciscis, CNR-IEOS
[/vc_column_text][vc_empty_space][vc_column_text]12:00 – 1:15 – Lunch[/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_empty_space height=”25px”][vc_separator type=”normal” color=”#303030″ thickness=”1″][vc_empty_space height=”25px”][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_column_text css=”.vc_custom_1530194309742{margin-bottom: 10px !important;}”]
[/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_empty_space height=”25px”][vc_separator type=”normal” color=”#303030″ thickness=”1″][vc_empty_space height=”25px”][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_column_text][/vc_column_text][vc_column_text css=”.vc_custom_1521135414627{margin-bottom: 10px !important;}”][/vc_column_text][vc_column_text]1:15 – 2:00 – Intracellular Aptamers
Donald Burke, Professor & Interim Chair, Dept. of Molecular Microbiology & Immunology, University of Missouri
[/vc_column_text][vc_empty_space height=”25px”][vc_column_text]2:00 – 2:30 – Enzyme modified DNA-surfactants: from nanoscale assembly to gene regulation
Jessica Rouge, Assistant Professor, University of Connecticut
[/vc_column_text][vc_empty_space height=”25px”][vc_column_text]2:30 – 3:00 – Modified aptamers enable quantitative sub-10-nm cellular DNA-PAINT imaging
Ralf Jungmann, Professor, Max Planck Institute of Biochemistry
[/vc_column_text][vc_empty_space height=”25px”][vc_column_text]3:00 – 3:20 – Single-particle tracking of receptor tyrosine kinases in living cells using DNA-based aptamers
Mike Hellemann, Professor, Goethe-University Frankfurt
[/vc_column_text][vc_empty_space height=”25px”][vc_column_text]3:20 – 3:50 – Break[/vc_column_text][vc_empty_space height=”25px”][vc_column_text]3:50 – 4:20 – Signal-tunable aptamer probe to guide precision tumor debulking
Youli Zu, Professor and Director of Hematorpathology, Houston Methodist Hospital
[/vc_column_text][vc_empty_space height=”25px”][vc_column_text]4:20 – 4:50 – RNA aptamers targeting transmembrane receptor tyrosine kinases (RTKs) act like RNAi in glioblastoma
Sorah Yoon, Staff Scientist, Beckman Research Institute of City of Hope
[/vc_column_text][vc_empty_space height=”25px”][vc_column_text]4:50 – 5:20 – C10.36 recognizes a surface spliceosomal complex andinduces aberrant splicing in B-cell lymphoma cells
Vaishali Pannu, Research Scientist I, Caris Life Sciences, Inc.
[/vc_column_text][vc_empty_space height=”25px”][vc_column_text]5:20 – 6:00 – Selection of RNaseA-mimicking DNAzymes with amines, imidazoles, and guanidines that cleave RNA: lessons for aptamer selections
David Perrin, Professor, Dept. of Chemistry, The University of British Columbia, Canada
[/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_empty_space height=”25px”][vc_separator type=”normal” color=”#303030″ thickness=”1″][vc_empty_space height=”25px”][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column width=”1/4″][vc_column_text]6:00 – 6:15 pm[/vc_column_text][/vc_column][vc_column width=”3/4″][vc_column_text css=”.vc_custom_1460450025108{margin-bottom: 10px !important;}”]
[/vc_column_text][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_empty_space height=”100px”][/vc_column][/vc_row][vc_row css_animation=”” row_type=”row” use_row_as_full_screen_section=”no” type=”full_width” angled_section=”no” text_align=”left” background_image_as_pattern=”without_pattern”][vc_column][vc_separator type=”normal”][/vc_column][/vc_row]